Now showing items 1-7 of 7

    • Parada Bustamante, Alexis; Lardone, María Cecilia; Madariaga, Marcia; Johnson, María Cecilia; Codner Dujovne, Ethel; Cassorla Goluboff, Fernando; Castro, Andrea (2012)
      Background: The etiology of hypospadias is multifactorial. Abnormal androgenic secretion and/or action during the development of external genitalia may be involved in the etiology of this congenital malformation. This study ...
    • Oróstica Arévalo, María Lorena; Lopez, John; Rojas, Israel; Rocco, Jocelyn; Diáz, Patricia; Reuqueń, Patricia; Cardenas, Hugo; Parada Bustamante, Alexis; Orihuela, Pedro A. (BioScientifica Ltd., 2014)
      In the rat oviduct, estradiol (E2) accelerates egg transport by a nongenomic action that requires previous conversion of E2 to methoxyestrogens via catechol-O-methyltranferase (COMT) and activation of estrogen receptor ...
    • Reuquén, Patricia; Oróstica Arévalo, María Lorena; Rojas, Israel; Díaz, Patricia; Parada Bustamante, Alexis; Orihuela, Pedro A. (Bioscientifica, 2015)
      Estradiol (E2) accelerates egg transport by a nongenomic action, requiring activation of estrogen receptor (ER) and successive cAMP and IP3 production in the rat oviduct. Furthermore, E2 increases IP3 production in primary ...
    • Lardone, María C.; Marengo, Altinay; Parada Bustamante, Alexis; Cifuentes, Lucía; Piottante, Antonio; Ebensperger, Mauricio; Valdevenito, Raúl; Castro, Andrea (2013)
      To determine the prevalence of South Amerindian Y chromosome in Chilean patients with spermatogenic failure and their association with classical and/or AZFc-partial Y chromosome deletions. We studied 400 men, 218 with ...
    • Oróstica Arévalo, María Lorena; López, John; Zúñiga, Lidia M.; Utz, Daniella; Díaz, Patricia; Reuquen, Patricia; Parada Bustamante, Alexis; Cárdenas, Hugo; Orihuela, Pedro A. (Wiley, 2014)
      Mating shuts down a 2-methoxyestradiol (2ME)-dependent, non-genomic activity that is responsible for accelerating egg transport in the rat oviduct. The aims of this work were to investigate the role of TGF1 in this 2ME-reduced ...
    • Parada Bustamante, Alexis; Orihuela, Pedro A.; Ríos, Mariana; Cuevas, Catherina A.; Oróstica Arévalo, María Lorena; Velásquez, Luis A.; Villalón, Manuel J.; Croxatto, Horacio B. (Society for Reproduction and Fertility, 2010)
      Estradiol (E2) accelerates oviductal egg transport through intraoviductal non-genomic pathways in unmated rats and through genomic pathways in mated rats. This shift in pathways has been designated as intracellular path ...
    • Quintana García, Oliver Brian (Universidad de Chile, 2018)
      Estudios epidemiológicos han determinado que la cantidad y la calidad de los espermatozoides en el eyaculado han disminuido en las últimas décadas. Uno de los parámetros afectados es el aumento en el porcentaje de ...